3-Hydroxypiperidine

Cas No:

6859-99-0

Synonyms:

3-Hydroxyhexahydropyridine;NSC   62082;Piperidin-3-ol;

Structural Formula:

Molecular Formula:

C5H11NO

Molecular Weight:

101.15

Technical Spec.:

Appearance

Yellowish to white crystalline solid

Purity

>=99%(GC)

Application

3-Hydroxypiperidine(CAS 6859-99-0)is an intermediate of Ibrutinib.

It can be used to produce 3-hydroxy-piperidine-1-carbonyl chloride at   the temperature of -65 °C. It will need reagent triethylamine and solvent   CH2Cl2 with the reaction time of 15 hours. The yield is about 87%.

3-Hydroxypiperidine is usually used for Synthesis of unsymmetrical   ureas,Synthesis of piperidine nucleoside analogs,Fluorination   reactions,Synthesis of substituted pyridines.