In solution that pH<4, carboxymethyl-β-cyclodextrin (CM-β-CD) solubility is low. But in pH>4 solution that carboxyl group dissociate, CM-β-CD can dissolved in water in any concentration. It has a good solubility in the human intestinal environment that pH is 6-7. CM-β-CD that has lower hemolysis than HP-β-CD can be used in prolonged release formulations.
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About Us
Tocosynth is the Chinese dosmetic susidiary company of Tocopharm,who mainly R&D and manufacturing chemicals raw materials based in Shanghai,China.Our company was established in 2012.