Optimized amide bond reaction using heterocyclic compounds and carboxylic acid TOHOKU UNIVERSITY DMAPO and Boc2O chemicals and a single reaction vessel IMAGE: OPTIMIZED REACTION CONDITIONS FOR AMIDE BOND FORMATION IN NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS USING CARBOXYLIC ACID REQUIRES ONLY 4-(N,N-DIMETHYLAMINO)PYRIDINE N-OXIDE (DMAPO) AND DI-TERTBUTYL DICARBONATE (BOC2O) IN A SINGLE REACTION VESSEL. A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without the use of heat or special equipment.

CPHI China 2024 Tocopharm will join in CPHI 2024 from June 19 to June 21 in Shanghai. CPHI & PMEC China is Asia’s leading pharmaceutical show for trading, knowledge sharing and networking. It spans all industry sectors along the pharmaceutical supply chain and is your one-stop platform to grow business in the 2nd largest pharma market in the world. CPHI & PMEC China 2024, with the co-located shows FDF, bioLIVE, Pharma Excipients, NEX and LABWORLD China, etc. is expected to draw 3,500+ exhibitors and hundreds and thousands of professionals from the pharmaceutical industry.

Topical Shows Promise in Treating Precancerous Cervical Condition April 09, 2024 by Michael Masciadrelli CIN Cervical cancer, often caused by persistent human papillomavirus (HPV) infections, remains a public health challenge worldwide despite falling diagnoses related to the success of the HPV vaccine in young adult women. More than 11,500 women in the U.S. are diagnosed with cervical cancer each year, and over 4,000 women die from it.

L-cyclodextrins synthesized in the lab for the first time A team of chemists at Northwestern University has successfully synthesized three L-cyclodextrins in the lab for the first time. In their study, published in the journal Nature Synthesis, the group used a one-pot strategy to achieve the feat.

Pods, profitability, and plant growth regulators Over the past few years, farmers have shown an increased interest in plant growth regulators and many have wondered what implications they have on yield.

Cotton PGR decisions need to start early Never too early to start considering the factors that dictate the use of plant growth regulators in cotton.Past research has shown that there's no interaction between plant growth regulator and nitrogen application strategies on yield and fiber quality. KNOWING THE AGGRESSIVENESS of your cotton variety and environmental conditions during the production season are important in making plant growth regulator application decisions.